Article ID: MTJPAM-D-23-00038

Title: QSPR analysis of antiparkinson’s drugs with degree based topological indices

Montes Taurus J. Pure Appl. Math. / ISSN: 2687-4814

Article ID: MTJPAM-D-23-00038; Volume 6 / Issue 3 / Year 2024, Pages 239-254

Document Type: Research Paper

Author(s): ‪Kalpana Ramesh ^a , Shobana Loganathan ^b , Ismail Naci Cangul ^c

^aDepartment of Mathematics, College of Engineering and Technology, SRM Institute of Science and Technology, SRM Nagar, Kattankulathur – 603 203,Tamil Nadu, India

^bDepartment of Mathematics, College of Engineering and Technology, SRM Institute of Science and Technology, SRM Nagar, Kattankulathur – 603 203,Tamil Nadu, India

^cDepartment of Mathematics, Bursa Uludag University, Gorukle 16059 Bursa, Turkey

Received: 10 November 2023, Accepted: 4 May 2024, Published: 2 July 2024

Corresponding Author: Ismail Naci Cangul (Email address: cangul@uludag.edu.tr)

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Abstract

The behaviour of some of the physico-chemical properties of anti-Parkinson’s disease drugs are statistically analysed which are targeted to reduce the effects of the severe symptoms especially body shaking. In this paper, the QSPR analysis of topological indices on various drugs are discussed and also shown that the topological indices are highly correlated with the physical and chemical properties of anti-Parkinson’s drugs. The analysis might provide the details for chemical and pharmaceutical industry to obtain the significance details through quantitative methods rather than practically experimenting it.

Keywords: Parkinson’s disease, anti drugs, topological indices, correlation coefficient, significance

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